The Sotriffer Group - The Sotriffer Group: Computational Medicinal Chemistry

Prof. Dr. Christoph Sotriffer

Universität Würzburg
Pharmaceutical and Medicinal Chemistry
Institute of Pharmacy and Food Chemistry
Am Hubland
97074 Würzburg

Phone: +49 (0) 931 31- 85443
christoph.sotriffer@uni-wuerzburg.de

Administrative support

Martina Weidinger

Phone: +49 (0) 931 31- 89276
martina.weidinger@uni-wuerzburg.de

Welcome

Explore with us the fascinating world of computational medicinal chemistry, from structure-based drug design and virtual screening to machine learning and molecular dynamics simulations, discover how to target enzymes and GPCRs, and appreciate the importance of the interplay between theory and experiment in drug discovery.

Overview: computational medicinal chemistry / Computer-Aided Drug Design

Just published

“Structural Optimization of Covalent Inhibitors for Deubiquitinase ChlaDUB1 of Chlamydia trachomatis as Antibiotic Agents”
T. Zimmermann, J. Feng. S. Fischer, L. Janaína de Campos, F. Ramos Pinheiro, C. Sotriffer, M. Conda-Sheridan and M. Decker
J. Med. Chem. 68 (5) (2025) 5400–5425
DOI: 10.1021/acs.jmedchem.4c02464

“High Affinity Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma cruzi, Burkholderia pseudomallei, and Legionella pneumophila─A Comparison.”
T. Lohr, C. Herbst, N. M. Bzdyl, C. Jenkins, N. J. Scheuplein, W. O. Sugiarto, J. J. Whittaker, A. Guskov, I. Norville, U. A. Hellmich, F. Hausch, M. Sarkar-Tyson, C. Sotriffer and U. Holzgrabe
ACS Infect. Dis. 10 (10) (2024) 3681-3691
DOI: 10.1021/acsinfecdis.4c00553

For more papers, please visit our "Publications"

Hubland Süd, Geb. C7

The Sotriffer Group: Computational Medicinal Chemistry

For more papers, please visit our "Publications"

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