Christoph Spangardt and team develop prototypes of autoinjectors for drug substances with slow dissolution rates. Congratulations for a manuscript at the interface of pharmaceutics and medical device development!more
Congratulations to Eduardo for winning the second poster prize at the
EUREKA 2022 17th International GSLS student symposium in Würzburg!
Jonas & team report on the in vivo impact of bile on drug absorption. Congratulations on this excellent teamwork!
Congratulations to Niklas and team for their article "Polymer selection impacts the pharmaceutical profile of site-specifically conjugated Interferon-α2a" published in Journal of controlled release!
Congratulations to Jonas, Josef, & team! They developed an algorithm predicting bile and lipid interaction of poorly water-soluble drugs! Hopefully, it might complement/precede vastly complex experiments which are currently required along these lines!more
Matthias Beudert and team have reviewed the latest developments on soft tissue glues with a focus on fibrin-based systems.more
Merging bioresponsive release of insulin-like growth factor I with 3D printable thermogelling hydrogels05/24/2022
Congratulations to Matthias Beudert and team for their manuscript
"Merging bioresponsive release of insulin-like growth factor I with 3D printable thermogelling hydrogels" published in journal of controlled release.
Four of our PhD students attended the 2022 meeting of the local chapters of the controlled release society (Germany, BeNeLux, France) in Aachen. Our team members contributed to the stimulating conference with three oral talks and one elevator pitch, with Eduardo Merino Asumendi and Simon Hanio being awarded for the conference’s best talk and elevator pitch, respectively. Many thanks to Prof. Lammers and his team for the excellent organization.more
Congratulations to Niklas Hauptstein & team for their review ”Bioconjugation strategies and clinical implications of Interferon-bioconjugates“, published in the European Journal of Pharmaceutics and Biopharmaceutics. The article reviews available IFN drugs, their field and route of application, while also outlining available and future strategies for bioconjugation to further optimize pharmaceutical and clinical performances of all three available IFN classes.more
Congratualtions to Dorothee Haas, Niklas Hauptstein & team for their manuscript ‘Chemo-enzymatic PEGylation/POxylation of murine Interleukin-4’ published in Bioconjugate Chemistry!more
Niklas and our partners from the Haag, Schubert, and Sotriffer labs at FU Berlin, Universities of Jena and Würzburg, respectively, just published an article on Interferon bioconjugates using various polymers. The study is published in Biomacromolecules. One interesting focus is on the interaction of the polymers with the protein surface and to which extend this explaines the stability of the biopolymer.more
Award for best contributed talk goes to Jonasmore
Small-molecule team visits cooperation partners in Greecemore
Simon Hanio & team detailed colloidal dynamics of bile fluids in response to a poorly water soluble drug substance, Perphenazine. By combining readouts from DLS, SANS, AUC, NMR, and other methods they detailed exciting adaptations in morphology and, arguably surprisingly, these adaptations did not impact the fraction of free drug substance. Congratulations to this very detailed and accurate contribution!more
As of February 23, 2021 Katharina Dodt completed her PhD with the defense of her thesis entitled „Monitoring enzyme activity by using mass-encoded peptides and multiplexed detection“. Congratulations!!!more