Prof. Brunschweiger

Tel.: +49 (0) 931 / 31 - 82450
Room: 01.004

Address:
Institut für Pharmazie und Lebensmittelchemie
Am Hubland
D - 97074 Würzburg

Secretary: Mrs. Möhler, lieselotte.moehler@uni-wuerzburg.de

Research focus: Drug research with DNA-encoded libraries (DEL)

Development of DNA-barcoding strategies and encoded reaction methodology
Exploration of nanoheterogeneous reaction systems for DNA-encoded library synthesis
Design and synthesis of chemically diverse or target-focused DNA-encoded libraries
Selection of DNA-encoded libraries on target proteins for compound identification
Validation of compounds identified from DEL selection
TEAD-YAP inhibitor development
Development of chemistry and encoded library data analysis tools based on KNIME

Jan. 2023	University of Würzburg: Head of Chair Pharmaceutical and Medicinal Chemistry
Independent research
Feb. 2013 - Dec. 2022	Independent research group leader, TU Dortmund (DEL technology, micellar reactions, data science, TEAD-YAP inhibitors)
Postdoctoral research
Feb. 2010 – Jan. 2013	Post-doc with Prof. Jonathan Hall, ETH Zürich (microRNA target identification, microRNA inhibitors)
Aug. 2007 – Jan. 2010	Post-doc with Prof. Christa Müller, University of Bonn, with UCB Pharma (hit-to-lead for multitarget drugs)
Education and Qualification
Jan. 2020	Venia legendi, Habilitation for the subject “Medicinal Chemistry” (Faculty of Chemistry and Chemical Biology, TU Dortmund)
Sep. 2016	Qualification to head a biosafety level 1 laboratory
Aug. 2009	„Fachapotheker für Arzneimittelinformation“
Oct. 2003 – Jul. 2007	PhD thesis in the group of Prof. C. E. Müller, University of Bonn
Jul. 2002 – Jun. 2003	“3. Abschnitt der Pharmazeutischen Ausbildung”
Mar. 1998 – Jun. 2002	Study of Pharmacy, Pharmaceutical Institute, University of Kiel
Jul. 1999 – Aug. 1999	Internship with Prof. I. Ivanov, Pharmaceutical Institute, University of Sofia

coming soon