Prof. Brunschweiger
Lehrstuhl für Pharmazeutische und Medizinische Chemie
Research focus: Drug research with DNA-encoded libraries (DEL)
- Development of DNA-barcoding strategies and encoded reaction methodology
- Exploration of nanoheterogeneous reaction systems for DNA-encoded library synthesis
- Design and synthesis of chemically diverse or target-focused DNA-encoded libraries
- Selection of DNA-encoded libraries on target proteins for compound identification
- Validation of compounds identified from DEL selection
- TEAD-YAP inhibitor development
- Development of chemistry and encoded library data analysis tools based on KNIME
Jan. 2023 | University of Würzburg: Head of Chair Pharmaceutical and Medicinal Chemistry |
Independent research | |
Feb. 2013 - Dec. 2022 | Independent research group leader, TU Dortmund (DEL technology, micellar reactions, data science, TEAD-YAP inhibitors) |
Postdoctoral research | |
Feb. 2010 – Jan. 2013 | Post-doc with Prof. Jonathan Hall, ETH Zürich (microRNA target identification, microRNA inhibitors) |
Aug. 2007 – Jan. 2010 | Post-doc with Prof. Christa Müller, University of Bonn, with UCB Pharma (hit-to-lead for multitarget drugs) |
Education and Qualification | |
Jan. 2020 | Venia legendi, Habilitation for the subject “Medicinal Chemistry” (Faculty of Chemistry and Chemical Biology, TU Dortmund) |
Sep. 2016 | Qualification to head a biosafety level 1 laboratory |
Aug. 2009 | „Fachapotheker für Arzneimittelinformation“ |
Oct. 2003 – Jul. 2007 | PhD thesis in the group of Prof. C. E. Müller, University of Bonn |
Jul. 2002 – Jun. 2003 | “3. Abschnitt der Pharmazeutischen Ausbildung” |
Mar. 1998 – Jun. 2002 | Study of Pharmacy, Pharmaceutical Institute, University of Kiel |
Jul. 1999 – Aug. 1999 | Internship with Prof. I. Ivanov, Pharmaceutical Institute, University of Sofia |
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