Publications
Just Published
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Investigations Into Chemically Stabilized Four-Letter DNA for DNA-Encoded Chemistry in Frontiers in Chemistry (2022). 10
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Reagent-Based Scaffold Diversity for DNA-Encoded Library Design: Solid Phase Synthesis of DNA-Tagged sp3-Rich Heterocycles by SnAP Chemistry in Organic Letters (2022). 24(6) 1383–1387.
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Navigating chemical reaction space – application to DNA-encoded chemistry in Chem. Sci. (2022). 13(37) 11221–11231.
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Functional Group Tolerance of a Micellar on-DNA SuzukitextendashMiyaura Cross-Coupling Reaction for DNA-Encoded Library Design in The Journal of Organic Chemistry (2021). 86(24) 17930–17935.
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Copper(I/II)-Promoted Diverse Imidazo[1,2-\($\upalpha$\)]pyridine Synthesis on Solid-Phase Bound DNA Oligonucleotides for Encoded Library Design in Organic Letters (2021). 23(14) 5480–5484.
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Towards DNA-Encoded Micellar Chemistry: DNA-Micelle Association and Environment Sensitivity of Catalysis in Chemistry textendash A European Journal (2021). 27(39) 10048–10057.
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TEADtextendashYAP Interaction Inhibitors and MDM2 Binders from DNA-Encoded Indole-Focused Ugi Peptidomimetics in Angewandte Chemie International Edition (2020). 59(46) 20338–20342.
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Screening of metal ions and organocatalysts on solid support-coupled DNA oligonucleotides guides design of DNA-encoded reactions in Chem. Sci. (2019). 10(45) 10481–10492.
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Synthesis of DNA-coupled isoquinolones and pyrrolidines by solid phase ytterbium- and silver-mediated imine chemistry in Med. Chem. Commun. (2019). 10(7) 1082–1093.
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Micellar Bronsted Acid Mediated Synthesis of DNA-Tagged Heterocycles in Journal of the American Chemical Society (2019). 141(26) 10546–10555.
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DNA-encoded libraries – an efficient small molecule discovery technology for the biomedical sciences in Biological Chemistry (2018). 399(7) 691–710.
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Design and synthesis of DNA-encoded libraries based on a benzodiazepine and a pyrazolopyrimidine scaffold in Med. Chem. Commun. (2016). 7(10) 1957–1965.
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Chemical Biology Probes from Advanced DNA-encoded Libraries in ACS Chemical Biology (2016). 11(2) 296–307.
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Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC in Chem. Commun. (2016). 52(1) 156–159.
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8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors in Bioorganic \&\($\mathsemicolon$\) Medicinal Chemistry (2016). 24(21) 5462–5480.
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8-Benzyltetrahydropyrazino[2,1-f]purinediones: Water-Soluble Tricyclic Xanthine Derivatives as Multitarget Drugs for Neurodegenerative Diseases in ChemMedChem (2014). n/a-n/a.
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1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases in Bioorganic \&\($\mathsemicolon$\) Medicinal Chemistry (2013). 21(23) 7435–7452.
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Virtual Screening Identifies Novel Sulfonamide Inhibitors of ecto-5’-Nucleotidase in Journal of Medicinal Chemistry (2012). 55(14) 6576–6581.
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P2 Receptors Activated by Uracil Nucleotides - An Update in Current Medicinal Chemistry (2006). 13(3) 289–312.
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Medizinische Chemie der Diuretika: Entwicklung einer erfolgreichen Wirkstoffgruppe in Pharmazie in unserer Zeit (2006). 35(4) 310–320.
Currently under update!