Erik Endres

Publikationen

“MD-Based Assessment of Covalent Inhibitors in Noncovalent Association Complexes: Learning from Cathepsin K as a Test Case”
E. Endres, N. Yuan Chen and C. Sotriffer
J. Chem. Inf. Model. (2023) Article ASAP
DOI: 10.1021/acs.jcim.3c00061

"Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation"
M. Scheiner, A. Sink, M. Hoffmann, C. Vrigneau, E. Endres, A. Carles, C. Sotriffer, T. Maurice and M. Decker
J. Am. Chem. Soc. 144 (7) (2022) 3279-3284
DOI: 10.1021/jacs.1c13492

"Warhead Reactivity Limits the Speed of Inhibition of the Cysteine Protease Rhodesain"
P. Johe, S. Jung, E. Endres, C. Kersten, C. Zimmer, W. Ye, C. Sönnichsen, U. A. Hellmich, C. Sotriffer, T. Schirmeister and H. Neuweiler
ACS Chem. Biol. 16 (4) (2021) 661–670
DOI: 10.1021/acschembio.0c00911

"Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an  Alzheimer’s Disease Mouse Model"
M. Hoffmann, C. Stiller, E. Endres, M. Scheiner, S. Gunesch, C. Sotriffer, T. Maurice, M. Decker
J. Med. Chem. 62 (20) (2019) 9116-9140
DOI: 10.1021/acs.jmedchem.9b01012