AK Sotriffer

    Erik Endres

    M.Sc. FOKUS Chemie, Doktorand

    Institut für Pharmazie und Lebensmittelchemie
    Am Hubland, Zimmer e00.001
    97074 Würzburg

    Tel.: +49 (931) 31-82697
    E-Mail: erik.endres@siehe_unten

    Bitte den Domain Namen in der e-mail Adresse zu uni-wuerzburg.de ändern




    “MD-Based Assessment of Covalent Inhibitors in Noncovalent Association Complexes: Learning from Cathepsin K as a Test Case”
    E. Endres, N. Yuan Chen and C. Sotriffer
    J. Chem. Inf. Model. 63 (10) (2023) 3186-3197
    DOI: 10.1021/acs.jcim.3c00061

    "Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer’s Disease Mouse Model upon Irradiation"
    M. Scheiner, A. Sink, M. Hoffmann, C. Vrigneau, E. Endres, A. Carles, C. Sotriffer, T. Maurice and M. Decker
    J. Am. Chem. Soc. 144 (7) (2022) 3279-3284
    DOI: 10.1021/jacs.1c13492

    "Warhead Reactivity Limits the Speed of Inhibition of the Cysteine Protease Rhodesain"
    P. Johe, S. Jung, E. Endres, C. Kersten, C. Zimmer, W. Ye, C. Sönnichsen, U. A. Hellmich, C. Sotriffer, T. Schirmeister and H. Neuweiler
    ACS Chem. Biol. 16 (4) (2021) 661–670
    DOI: 10.1021/acschembio.0c00911

    "Highly Selective Butyrylcholinesterase Inhibitors with Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an  Alzheimer’s Disease Mouse Model"
    M. Hoffmann, C. Stiller, E. Endres, M. Scheiner, S. Gunesch, C. Sotriffer, T. Maurice, M. Decker
    J. Med. Chem. 62 (20) (2019) 9116-9140
    DOI: 10.1021/acs.jmedchem.9b01012