Bile Is a Selective Elevator for Mucosal Mechanics and Transport
03.11.2023Simon Hanio & team detailed how bile transiently alters mucosal biomechanics and how it promotes transports through mucus. By combining readouts from NMR, Brillouin Microscopy, Differential dynamic microscopy, and others methods, they defined the critical role of bile in the mucus transport drugs that interact with bile. Congratulations on this interdisciplinary team effort!
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.3c00550
Reprinted with permission from
Hanio S, Möllmert S, Möckel C, Choudhury S, Höpfel AI, Zorn T, Endres S, Schlauersbach J, Scheller L, Keßler C, Scherf-Clavel O, Bellstedt P, Schubert US, Pöppler AC, Heinze KG, Guck J, Meinel L. Bile Is a Selective Elevator for Mucosal Mechanics and Transport. Mol Pharm. 2023 Dec 4;20(12):6151-6161. doi: 10.1021/acs.molpharmaceut.3c00550.
Copyright 2023 American Chemical Society.
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