News

On the 6th of November, Yoshinori Kato and Yusuke Iwasaki from the Hoshi University visited our labs and gave a talk about the detection of oxidative stress using LC-MS/MS. We look forward to the next meet-up!

Lea Hofman, Timo Keim, Oskar Steinlein and Tobias Stepic visited our partner university, the Hoshi University, in Tokyo in October 2024.

Prisca & team demonstrated an elegant approach to immobilize myostatin antagonists on extracellular matrices, with immediate relevance for bone turnover. Congratulations!!

On 03 July 2024, Matthias Ruopp defended his PhD thesis entitled "Biochemical, enzymatic and mechanical optimization of drug candidates and drug delivery for inflammation related diseases". Amazing job and all the best for the future!

Congratulations to Debora and team! They published their sensors, differentiating tumor biopsies from healthy tissues - in less than 10 minutes. These sensors hold promise to substantially reduce surgery times, as the decision to continue tissue removal might be shifted into the operation theater!

On 02 July 2024, Joel van Dorp completed his PhD with the defense of his dissertation entitled "Site-specific biomolecule modification for directed surface attachment". Congratulations!

After developing Matrix Metalloproteinase 13 cleavable peptides, Prisca & team have published a blueprint for the systematic development of protease sensitive linkers. Congratulations!

We congratulate Alena and team for publishing their work on PEGylated Aplysia punctata ink toxin as a potential tumor therapeutic agent!

On 01 February 2024, Simon Hanio defended his PhD thesis entitled "The impact of bile on intestinal permeability of drug substances". Great job!

Oskar Steinlein, Timo Keim, and Lorenz Meinel visited our partner university in Tokyo in December 2023.

On November 10, 2023, Dr. Niklas Hauptstein was awarded the VAA Foundation's Excellence Prize at the VAA Annual Conference in Mannheim. Dr. Hauptstein completed his doctorate under Prof. Lorenz Meinel at the University of Würzburg, Faculty of Chemistry and Pharmacy, on the topic of "Site directed molecular design and performances of Interferon-α2a and Interleukin-4 bioconjugates with PEG alternative polymers". The prize is awarded for outstanding dissertations.

Simon Hanio & team detailed how bile transiently alters mucosal biomechanics and how it promotes transports through mucus. By combining readouts from NMR, Brillouin Microscopy, Differential dynamic microscopy, and others methods, they defined the critical role of bile in the mucus transport drugs that interact with bile. Congratulations on this interdisciplinary team effort!

Congratulations to Giorgia Gerolimetto and Kirstin Meiners, awarded for their shared poster “Evaluation of design spaces for Lipid nanoparticles and mRNA formulations” at the DPhG Annual Meeting 2023 in Tübingen. Many thanks to the DPhG committee for the excellent organization!

Congrats to Kirstin and team for publishing site-specific modification strategies for Alteplase!

Congrats to Matthias Ruopp and Coworkers for publishing a novel FAP targeting Interleukin-4 Bioconjugate!