News

On 01 February 2024, Simon Hanio defended his PhD thesis entitled "The impact of bile on intestinal permeability of drug substances". Great job!

Oskar Steinlein, Timo Keim, and Lorenz Meinel visited our partner university in Tokyo in December 2023.

On November 10, 2023, Dr. Niklas Hauptstein was awarded the VAA Foundation's Excellence Prize at the VAA Annual Conference in Mannheim. Dr. Hauptstein completed his doctorate under Prof. Lorenz Meinel at the University of Würzburg, Faculty of Chemistry and Pharmacy, on the topic of "Site directed molecular design and performances of Interferon-α2a and Interleukin-4 bioconjugates with PEG alternative polymers". The prize is awarded for outstanding dissertations.

Simon Hanio & team detailed how bile transiently alters mucosal biomechanics and how it promotes transports through mucus. By combining readouts from NMR, Brillouin Microscopy, Differential dynamic microscopy, and others methods, they defined the critical role of bile in the mucus transport drugs that interact with bile. Congratulations on this interdisciplinary team effort!

Congratulations to Giorgia Gerolimetto and Kirstin Meiners, awarded for their shared poster “Evaluation of design spaces for Lipid nanoparticles and mRNA formulations” at the DPhG Annual Meeting 2023 in Tübingen. Many thanks to the DPhG committee for the excellent organization!

Congrats to Kirstin and team for publishing site-specific modification strategies for Alteplase!

Congrats to Matthias Ruopp and Coworkers for publishing a novel FAP targeting Interleukin-4 Bioconjugate!

On 26 June 2023 Matthias Beudert defended his PhD thesis "Bioinspired Modification and Functionalization of Hydrogels for Applications in Biomedicine." Well done!

Congratulations to Björn & team for the development of peptide based matrix-metalloproteinase responsive sensors for the machine-independent detection of inflammations of the periodontium!

Shoutout to Alena & team, who published a paper on the design of PEGylated VEGF bioconjugates. Well done!

Björn & team have published an article on the drug release of cytokines depending on the upregulation of Matrix Metalloproteinases in inflammation. Congratulations!

Matthias Ruopp developed the first transdermal therapeutic system (TTS) for therapeutic gases! His TTS generates the gas and releases it through a special membrane across the skin into the underlying tissues. A patent is pending, he published this contribution in the Journal of Controlled Release (JCR).

Congratulations to Lena Scheller & team. She developed a powder-form microemulsion adsorbed to a metalloorganic framework (MOF). Once the powder reaches the stomach, the MOF disintegrates, releasing the adsorbed molecules that readily form a microemulsion. The concept might be an interesting oral delivery form for poorly water-soluble drugs. A patent is pending, the article has been published in the European Journal of Pharmaceutics and Biopharmaceutics (EJPB).

Prisca visited our colleague at the University of Chile in Santiago de Chile . She presented her work entitled: "Drug Delivery of a Myostatin-inhibiting Peptide".

Congrats for Martina and Eleonora for the development of an amber triggered azobenzene photo switch for modulation of peptide secondary structure!